Similar to Asian ginseng, toal ginsenosides accounts for 5%～10% of the dried weight of American ginseng, however, its composition of ginsenosides differs largely from those in Asian ginseng, resulting into differnet pharmacological actions.

Major pharmacological activities of American ginseng are listed as follows:

1. Cardiovascular system: a. improve myocardial performance and its resistance to ischemia; b. anti-arrhythmia; c. anti-shock; d. anti-atherosclerosis.
2. Physical performance: a. anti-anoxia; b. anti-fatigue; c. increase endurance towards coldness and hotness; d. anti-thirst and anti-starvation.
3. Stimulate hematopoiesis (blood production through bone marrow)
4. induce tranquility
5. reduce blood glucose (hypoglycemic)
6. boost immune system